| Product Name | Anti-Phospho-HDAC3(Ser424) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser424 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HDAC3 |
|---|---|
| Gene Synonyms | HD3 RPD3 KDAC3 RPD3-2 HDAC3 |
| Gene Full Name | Histone deacetylase 3 |
| Gene Summary | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | HD3 HDAC 3 HDAC3 HDAC3_HUMAN Histone deacetylase 3 RPD3 2 RPD3 RPD3-2 SMAP45 |
| Molecular Weight(MW) | 49 kDa |
| Cellular Localization | Nucleus. Cytoplasm. Cytoplasm>Cytosol. |
| SwissProt ID | O15379 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
