| Product Name | Anti-Phospho-ATF1(Ser63) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser63 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATF1 |
|---|---|
| Gene Synonyms | TREB36 EWS-ATF1 FUS/ATF-1 |
| Gene Full Name | activating transcription factor 1 |
| Gene Summary | This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010] |
| Alternative Names | Activating transcription factor 1 antibody ATF 1 antibody atf1 antibody ATF1 EWS fusion gene antibody ATF1 FUS fusion gene antibody ATF1_HUMAN antibody cAMP dependent transcription factor 1 antibody cAMP-dependent transcription factor ATF-1 antibody Cyclic AMP dependent transcription factor ATF 1 antibody Cyclic AMP dependent transcription factor ATF1 antibody Cyclic AMP-dependent transcription factor ATF-1 antibody EWS AFT1 antibody FUS ATF 1 antibody FUS/ATF 1 antibody Protein TREB36 antibody RNA binding protein activating transcription factor 1 fusion protein antibody TREB 36 antibody TREB36 antibody TREB36 protein antibody |
| Molecular Weight(MW) | 29 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P18846 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
