| Product Name | Anti-Phospho-ATF1 (Ser198) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser198 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATF1 |
|---|---|
| Gene Synonyms | TREB36 EWS-ATF1 FUS/ATF-1 |
| Gene Full Name | activating transcription factor 1 |
| Gene Summary | This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010] |
| Alternative Names | Activating transcription factor 1 ATF 1 atf1 ATF1 EWS fusion gene ATF1 FUS fusion gene ATF1_HUMAN cAMP dependent transcription factor 1 cAMP-dependent transcription factor ATF-1 Cyclic AMP dependent transcription factor ATF 1 Cyclic AMP dependent transcription factor ATF1 Cyclic AMP-dependent transcription factor ATF-1 EWS AFT1 FUS ATF 1 FUS/ATF 1 Protein TREB36 RNA binding protein activating transcription factor 1 fusion protein TREB 36 TREB36 TREB36 protein |
| Molecular Weight(MW) | 29 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P18846 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
