| Gene Symbol |
SGK1
|
| Gene Synonyms |
SGK |
| Gene Full Name |
serum/glucocorticoid regulated kinase 1 |
| Gene Summary |
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009] |
| Alternative Names |
OTTHUMP00000017247 Serine/threonine protein kinase SGK Serine/threonine protein kinase Sgk1 Serine/threonine-protein kinase Sgk1 Serum and glucocorticoid regulated kinase Serum/glucocorticoid regulated kinase 1 Serum/glucocorticoid regulated kinase Serum/glucocorticoid-regulated kinase 1 SGK 1 SGK SGK1 Sgk1 variant i3 SGK1_HUMAN |
| Molecular Weight(MW) |
49 kDa |
| Cellular Localization |
Cell membrane,Cytoplasm,Endoplasmic reticulum,Membrane,Mitochondrion,Nucleus. |