ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Product Name | Anti-Phospho-JNK1/2/3 (Tyr185) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr185 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAPK8/MAPK9/MAPK10 |
|---|---|
| Gene Synonyms | JNK JNK1 PRKM8 SAPK1 JNK-46 JNK1A2 SAPK1c JNK21B1/2/JNK2 SAPK p54a JNK2A JNK2B PRKM9 JNK-55 SAPK1a JNK2BETA p54aSAPK JNK2ALPHA/JNK3 JNK3A PRKM10 SAPK1b p493F12 p54bSAPK |
| Gene Full Name | mitogen-activated protein kinase 8/mitogen-activated protein kinase 9/mitogen-activated protein kinase 10 |
| Gene Summary | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] |
| Alternative Names | C Jun kinase 2 c Jun N terminal kinase 1 c Jun N terminal kinase 2 c Jun N terminal kinase 3 c-Jun N-terminal kinase 1 JNK 46 JNK 55 JNK JNK-46 JNK1 JNK1A2 JNK2 JNK21B1/2 JNK2A JNK2ALPHA JNK2B JNK2BETA JNK3 alpha protein kinase JNK3 JNK3A Jun kinase JUN N terminal kinase MAP kinase 10 MAP kinase 8 MAP kinase 9 MAP kinase p49 3F12 MAPK 10 MAPK 8 MAPK 9 MAPK10 mapk8 MAPK9 Mitogen activated protein kinase 10 Mitogen activated protein kinase 8 Mitogen activated protein kinase 8 isoform JNK1 alpha1 Mitogen activated protein kinase 8 isoform JNK1 beta2 Mitogen activated protein kinase 9 Mitogen-activated protein kinase 8 MK08_HUMAN p493F12 p54a p54aSAPK p54bSAPK PRKM10 PRKM8 PRKM9 SAPK SAPK(beta) SAPK1 SAPK1a SAPK1b SAPK1c Stress activated protein kinase 1 Stress activated protein kinase 1a Stress activated protein kinase 1b Stress activated protein kinase 1c Stress activated protein kinase beta Stress activated protein kinase JNK1 Stress activated protein kinase JNK2 Stress activated protein kinase JNK3 Stress-activated protein kinase 1c Stress-activated protein kinase JNK1 c Jun kinase 2 C Jun N terminal kinase 2 c-Jun N-terminal kinase 2 JNK 55 JNK-55 JNK2 alpha JNK2 JNK2 beta JNK2A JNK2alpha JNK2B JNK2BETA Jun kinase MAP kinase 9 MAPK 9 Mapk9 Mitogen activated protein kinase 9 Mitogen-activated protein kinase 9 MK09_HUMAN P54a p54aSAPK PRKM9 Protein kinase mitogen-activated 9 SAPK alpha SAPK SAPK1a Stress activated protein kinase 1a Stress-activated protein kinase JNK2 c Jun kinase 3 c-Jun N-terminal kinase 3 cJun N terminal kinase 3 FLJ12099 FLJ33785 JNK3 alpha protein kinase JNK3 JNK3A MAP kinase 10 MAP kinase MAP kinase p49 3F12 MAPK 10 Mapk10 MGC50974 mitogen activated protein kinase 10 Mitogen-activated protein kinase 10 MK10_HUMAN p493F12 p54bSAPK PRKM10 protein kinase mitogen activated 10 SAPK1b Stress activated protein kinase 1b stress activated protein kinase beta Stress activated protein kinase JNK3 Stress-activated protein kinase JNK3 |
| Molecular Weight(MW) | 48 kDa/48 kDa/53 kDa |
| Cellular Localization | Cytoplasm, Nucleus, Synapse/Cytoplasm, Nucleus/Cytoplasm, Membrane, Mitochondrion, Nucleus. |
| SwissProt ID | P45983 |
|---|
ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
