| Product Name | Anti-Phospho-BLNK (Tyr96) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr96 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BLNK |
|---|---|
| Gene Synonyms | bca AGM4 BASH LY57 SLP65 BLNK-S SLP-65 |
| Gene Full Name | B cell linker |
| Gene Summary | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] |
| Alternative Names | AGM4 B cell adapter containing SH2 domain protein B cell adapter containing Src homology 2 domain protein B cell adaptor containing SH2 domain B cell linker B cell linker protein B cell-specific adaptor protein B-cell activation B-cell adapter containing a SH2 domain protein B-cell adapter containing a Src homology 2 domain protein B-cell linker protein BASH Bca BLNK BLNK s BLNK_HUMAN Cytoplasmic adapter protein Ly 57 Ly57 Lymphocyte antigen 57 Lyw 57 Lyw57 MGC111051 SH2 domain-containing leukocyte protein 65-KD SLP 65 SLP-65 SLP65 Src homology [SH2] domain-containing leukocyte protein of 65 kD Src homology 2 domain containing leukocyte protein of 65 kDa Src homology 2 domain-containing leukocyte protein of 65 kDa |
| Molecular Weight(MW) | 50 kDa |
| Cellular Localization | Cell membrane, Cytoplasm, Membrane. |
| SwissProt ID | Q8WV28 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
