| Gene Symbol |
HDAC6
|
| Gene Synonyms |
HD6 JM21 CPBHM KDAC6 PPP1R90 |
| Gene Full Name |
histone deacetylase 6 |
| Gene Summary |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008] |
| Alternative Names |
CPBHM FLJ16239 HD 6 HD6 HDAC 6 HDAC6 HDAC6_HUMAN Histone deacetylase 6 (HD6) Histone deacetylase 6 JM 21 JM21 KIAA0901 OTTHUMP00000032398 OTTHUMP00000197663 PPP1R90 Protein phosphatase 1 regulatory subunit 90 |
| Molecular Weight(MW) |
131 kDa |
| Cellular Localization |
Cell projection, Cytoplasm, Cytoskeleton, Nucleus. |