ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Product Name | Anti-Phospho-PAK5/6 (Ser602/Ser560) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser602/Ser560 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PAK5/PAK6 |
|---|---|
| Gene Full Name | p21 (RAC1) activated kinase 5/p21 (RAC1) activated kinase 6 |
| Gene Summary | This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| Alternative Names | CDKN1A activated kinase 6 EC 2.7.1.37 p21 activated protein kinase 6 p21 protein (Cdc42/Rac)-activated kinase 6 p21(CDKN1A) activated kinase 6 p21-activated kinase 6 p21activated kinase 6 PAK 5 PAK 6 PAK-5 PAK-6 PAK5 Pak6 PAK6_HUMAN Serine threonine protein kinase PAK 6 Serine/threonine protein kinase PAK 6 Serine/threonine protein kinase PAK6 Serine/threonine-protein kinase PAK 6 EC 2.7.11.1 KIAA1264 MGC26232 p21 activated kinase 7 p21 protein (Cdc42/Rac)-activated kinase 7 p21(CDKN1A) activated kinase 7 p21-activated kinase 5 p21-activated kinase 7 PAK 5 PAK 7 PAK-5 PAK-7 PAK5 PAK7 PAK7_HUMAN Protein kinase PAK5 Serine/threonine protein kinase PAK 7 Serine/threonine-protein kinase PAK 7 |
| Molecular Weight(MW) | 81 kDa/75 kDa |
| Cellular Localization | Cytoplasm, Mitochondrion, Nucleus/Cytoplasm, Nucleus. |
| SwissProt ID | Q9P286 |
|---|
ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
