| Product Name | Anti-Phospho-FANCD2 (Ser222) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser222 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FANCD2 |
|---|---|
| Gene Synonyms | FA4 FAD FACD FAD2 FA-D2 FANCD |
| Gene Full Name | FA complementation group D2 |
| Gene Summary | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Alternative Names | DKFZp762A223 antibody FA 4 antibody FA D2 antibody FA4 antibody FAC D2 antibody FACD 2 antibody FACD antibody FACD2 antibody FACD2_HUMAN antibody FAD antibody FAD2 antibody FANC D2 antibody FANCD 2 antibody FANCD antibody FANCD2 antibody FANCONI ANEMIA COMPLEMENTATION GROUP D antibody Fanconi anemia complementation group D2 antibody Fanconi anemia group D2 protein antibody FANCONI PANCYTOPENIA TYPE 4 antibody FLJ23826 antibody OTTHUMP00000158853 antibody OTTHUMP00000207925 antibody Protein FACD2 antibody Type 4 Fanconi pancytopenia antibody |
| Molecular Weight(MW) | 164 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q9BXW9 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
