| Gene Symbol |
RBBP8
|
| Gene Synonyms |
RIM COM1 CTIP JWDS SAE2 JAWAD SCKL2 |
| Gene Full Name |
RB binding protein 8, endonuclease |
| Gene Summary |
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008] |
| Alternative Names |
COM1 antibody
COM1_HUMAN antibody
CtBP interacting protein antibody
CtBP-interacting protein antibody
CtIP antibody
DNA endonuclease RBBP8 antibody
JWDS antibody
RB binding protein 8 endonuclease antibody
RBBP-8 antibody
RBBP8 antibody
Retinoblastoma-binding protein 8 antibody
Retinoblastoma-interacting protein and myosin-like antibody
Rim antibody
SAE2 antibody
SCKL2 antibody
Sporulation in the absence of SPO11 protein 2 homolog antibody |
| Molecular Weight(MW) |
102 kDa |
| Cellular Localization |
Chromosome,Nucleus. |