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OM682350
Discount Price
OM682350-100ul
100ul
Product Profile
Product Name Anti-Phospho-STAT4 (Tyr693) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Tyr693
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol STAT4
Gene Synonyms DPMC
SLEB11
Gene Full Name signal transducer and activator of transcription 4
Gene Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Alternative Names Signal transducer and activator of transcription 4
SLEB11
STAT4
STAT4_HUMAN
Molecular Weight(MW) 86 kDa
Cellular Localization Cytoplasm,Nucleus.
Database Links
SwissProt ID Q14765
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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