| Gene Symbol |
GBF1
|
| Gene Synonyms |
CMT2GG CMTDI2 CMTDIA ARF1GEF |
| Gene Full Name |
golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| Gene Summary |
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010] |
| Alternative Names |
ARF1GEF BFA resistant GEF 1 BFA-resistant GEF 1 FLJ21263 FLJ21500 GBF1 GBF1_HUMAN golgi brefeldin A resistant guanine nucleotide exchange factor 1 Golgi specific brefeldin A resistance factor 1 Golgi specific Brefeldin A-resistance factor Golgi-specific brefeldin A-resistance guanine nucleotide exchange Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 KIAA0248 MGC134877 MGC134878 |
| Molecular Weight(MW) |
206 kDa |
| Cellular Localization |
Cytoplasm,Golgi apparatus,Lipid droplet,Membrane. |