| Product Name | Anti-Phospho-TMEM173/STING (Ser358) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser358 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STING1 |
|---|---|
| Gene Synonyms | ERIS MITA MPYS SAVI NET23 STING hMITA hSTING TMEM173 STING-beta |
| Gene Full Name | stimulator of interferon response cGAMP interactor 1 |
| Gene Summary | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
| Alternative Names | endoplasmic reticulum IFN stimulator antibody Endoplasmic reticulum interferon stimulator antibody ERIS antibody FLJ38577 antibody hMITA antibody hSTING antibody Mediator of IRF3 activation antibody MITA antibody Mitochondrial mediator of IRF3 activation antibody MPYS antibody N terminal methionine proline tyrosine serine plasma membrane tetraspanner antibody NET23 antibody Stimulator of interferon genes antibody Stimulator of interferon genes protein antibody STING antibody TM173_HUMAN antibody Tmem173 antibody Transmembrane protein 173 antibody |
| Molecular Weight(MW) | 42 kDa |
| Cellular Localization | Cell membrane,Cytoplasm,Cytoplasmic vesicle,Endoplasmic reticulum,Golgi apparatus,Membrane,Mitochondrion,Mitochondrion outer membrane. |
| SwissProt ID | Q86WV6 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
