| Gene Symbol |
MAP3K14
|
| Gene Synonyms |
HS NIK HSNIK IMD112 FTDCR1B |
| Gene Full Name |
mitogen-activated protein kinase kinase kinase 14 |
| Gene Summary |
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008] |
| Alternative Names |
MAP3K14 FTDCR1B HS HsNIK M3K14_HUMAN Map3k14 Mitogen activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 14 NF kappa beta inducing kinase NF-kappa-beta-inducing kinase NIK Serine/threonine-protein kinase NIK |
| Molecular Weight(MW) |
104 kDa |
| Cellular Localization |
Cytoplasm. |