| Product Name | Anti-Phospho-PPP1CA (Thr320) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Thr320 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PPP1CA |
|---|---|
| Gene Synonyms | PP1A PP-1A PPP1A PP1alpha |
| Gene Full Name | protein phosphatase 1 catalytic subunit alpha |
| Gene Summary | The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2020] |
| Alternative Names | Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit Catalytic subunit EC 3.1.3.16 MGC15877 MGC1674 PP 1A PP-1A PP1A PP1A_HUMAN PP1alpha PP2C ALPHA PP2CA Ppp1ca Protein Phosphatase 2C Alpha Isoform Serine threonine protein phosphatase PP1 alpha catalytic subunit Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
| Molecular Weight(MW) | 38 kDa |
| Cellular Localization | Nucleus, nucleoplasm, nucleolus, cytoplasm |
| SwissProt ID | P62136 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
