| Gene Symbol |
TNFAIP3
|
| Gene Synonyms |
A20 AISBL AIFBL1 OTUD7C TNFA1P2 |
| Gene Full Name |
TNF alpha induced protein 3 |
| Gene Summary |
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012] |
| Alternative Names |
A20 AISBL MGC104522 MGC138687 MGC138688 OTU domain containing protein 7C OTU domain-containing protein 7C OTUD7C Putative DNA binding protein A20 Putative DNA-binding protein A20 TNAP3_HUMAN TNF alpha-induced protein 3 TNFA1P2 TNFAIP 3 TNFAIP3 (A20) TNFAIP3 Tumor necrosis factor alpha induced protein 3 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor induced protein 3 Tumor necrosis factor inducible protein A20 tumor necrosis factor alpha-induced protein 3 Zinc finger protein A20
|
| Molecular Weight(MW) |
90 kDa |
| Cellular Localization |
Cytoplasm, Lysosome, Nucleus |