| Product Name | Anti-Phospho-TUBA1/3/4 (Tyr272) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr272 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TUBA1A/TUBA1B/TUBA1C/TUBA3E/TUBA4A |
|---|---|
| Gene Synonyms | LIS3 TUBA3 CDCBM16 B-ALPHA-1/K-ALPHA-1/TUBA6 bcm948 OZEMA24/ALS22 TUBA1 CMYO26 SPAX11 FTDALS9 OZEMA23 H2-ALPHA |
| Gene Full Name | tubulin alpha 1a/tubulin alpha 1b/tubulin alpha 1c/tubulin alpha 3e/tubulin alpha 4a |
| Gene Summary | Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017] |
| Alternative Names | Alpha tubulin ubiquitous Alpha-tubulin ubiquitous K alpha 1 TBA1B_HUMAN TUBA1B Tubulin alpha 1B Tubulin alpha 1B chain Tubulin alpha ubiquitous Tubulin alpha ubiquitous chain Tubulin alpha-1B chain Tubulin alpha-ubiquitous chain Tubulin K alpha 1 Tubulin K-alpha-1 Alpha-tubulin 1 ALS22 B ALPHA 1 bA408E5.3 H2 ALPHA Hum a tub1 Hum a tub2 LIS3 MGC171407 MGC55332 TBA4A_HUMAN Testis-specific alpha-tubulin TUBA1 TUBA1A tuba1l Tuba4a Tubulin alpha 1 chain Tubulin alpha Tubulin alpha-1 chain tubulin alpha-1B chain Tubulin alpha-4A chain Tubulin H2-alpha Tubulin alpha 1 (testis specific) tubulin alpha 1 like Tubulin alpha 4a Tubulin alpha testis-specific Tubulin alpha-1 Alpha-tubulin 2 Alpha-tubulin 3C/D alpha-tubulin isotype H2-alpha H2-ALPHA TBA3C_HUMAN TUBA2 TUBA3C TUBA3D Tubulin alpha 2 Tubulin alpha 2 chain Tubulin alpha 3c Tubulin alpha-2 chain Tubulin alpha-3C/D chain Alpha tubulin 3 Alpha-tubulin 3 B alpha 1 FLJ25113 LIS3 TBA1A_HUMAN TUBA1A TUB |
| Molecular Weight(MW) | 50 kDa |
| Cellular Localization | Cell projection,Cilium,Cytoplasm,Cytoskeleton,Flagellum,Microtubule./Cytoplasm,Cytoskeleton,Microtubule. |
| SwissProt ID | Q71U36 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
