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OM682912
Discount Price
OM682912-100ul
100ul
Product Profile
Product Name Anti-Phospho-HP1 alpha (Ser92) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH
Modification p-Ser92
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CBX5
Gene Synonyms HP1
HP1A
HEL25
HP1alpha
Gene Full Name chromobox 5
Gene Summary This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Alternative Names Antigen p25
CBX5
CBX5_HUMAN
CG8409
Chromobox 5
Chromobox homolog 5 (HP1 alpha homolog
Drosophila)
Chromobox homolog 5
Chromobox protein homolog 5
Epididymis luminal protein 25
HEL25
Heterochromatin protein 1 alpha
Heterochromatin protein 1
Heterochromatin protein 1 homolog alpha
HP1 alpha
HP1 alpha homolog
HP1
HP1A
HP1Hs alpha
Su(var)205
Molecular Weight(MW) 22 kDa
Cellular Localization Centromere,Chromosome,Nucleus.
Database Links
SwissProt ID P45973
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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