| Gene Symbol |
STK3
|
| Gene Synonyms |
KRS1 MST2 |
| Gene Full Name |
serine/threonine kinase 3 |
| Gene Summary |
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Alternative Names |
0610042I06Rik EC 2.7.11.1 FLJ90748 KB 1458E12.1 Kinase responsive to stress 1 KRS1 Mammalian STE20 like protein kinase 2 Mammalian STE20-like protein kinase 2 Mammalian sterile 20-like 2 Mess1 MST MST-2 MST2 Mst3 Serine/threonine kinase 3 (STE20 homolog yeast) Serine/threonine kinase 3 (Ste20 yeast homolog) Serine/threonine kinase 3 Serine/threonine protein kinase 3 Serine/threonine protein kinase Krs1 Serine/threonine-protein kinase 3 Serine/threonine-protein kinase Krs-1 STE20 like kinase MST2 STE20-like kinase MST2 Stk3 STK3_HUMAN wu:fc19e11 zgc:55383 |
| Molecular Weight(MW) |
56 kDa |
| Cellular Localization |
Cytoplasm,Cytoskeleton,Nucleus. |