| Gene Symbol |
KAT2B
|
| Gene Synonyms |
CAF PCAF P/CAF |
| Gene Full Name |
lysine acetyltransferase 2B |
| Gene Summary |
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008] |
| Alternative Names |
CAF CREBBP associated factor GCN5 GCN5L GCN5L1 Histone acetylase PCAF Histone acetyltransferase KAT2B Histone acetyltransferase PCAF K(lysine) acetyltransferase 2B KAT2B KAT2B_HUMAN Lysine acetyltransferase 2B P P/CAF p300/CBP associated factor P300/CBP-associated factor Pcaf |
| Molecular Weight(MW) |
93 kDa |
| Cellular Localization |
Cytoplasm,Cytoskeleton,Nucleus. |