| Product Name | Anti-Phospho-PABP2 (Ser150) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser150 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PABPN1 |
|---|---|
| Gene Synonyms | OPMD PAB2 PABII PABP2 PABP-2 |
| Gene Full Name | poly(A) binding protein nuclear 1 |
| Gene Summary | This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010] |
| Alternative Names | Nuclear poly(A)-binding protein 1 OPMD PAB2 PABII PABP 2 pABP-2 PABP2 PABP2_HUMAN PABPII Pabpn1 poly(A) binding protein nuclear 1 Poly(A)-binding protein 2 Poly(A)-binding protein II PolyA binding protein II Polyadenylate-binding nuclear protein 1 Polyadenylate-binding protein 2 |
| Molecular Weight(MW) | 33 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q86U42 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
