| Product Name | Anti-Phospho-TDP43 (Ser409/Ser410) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser409/Ser410 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TARDBP |
|---|---|
| Gene Synonyms | ALS10 TDP-43 |
| Gene Full Name | TAR DNA binding protein |
| Gene Summary | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] |
| Alternative Names | ALS10 OTTHUMP00000002171 OTTHUMP00000002172 OTTHUMP00000002173 TADBP_HUMAN TAR DNA binding protein 43 TAR DNA binding protein TAR DNA-binding protein 43 TARDBP TDP 43 TDP-43 TDP43 |
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Cytoplasm, Mitochondrion, Nucleus. |
| SwissProt ID | Q13148 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
