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OM683252
Discount Price
OM683252-100ul
100ul
Product Profile
Product Name Anti-Phospho-MER/TYRO3 (Tyr749/Tyr681) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH
Modification p-Tyr749/Tyr681
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MERTK/TYRO3
Gene Synonyms MER
RP38
c-Eyk
c-mer
Tyro12
BYK
Dtk
RSE
Rek
Sky
Tif
Etk-2
Gene Full Name MER proto-oncogene, tyrosine kinase/TYRO3 protein tyrosine kinase
Gene Summary This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]/The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]
Alternative Names Brt
BYK
DTK
Etk-2
protein tyrosine kinase 3
Rek
RSE
SKY
Tif
tyro3
TYRO3 protein tyrosine kinase
TYRO3_HUMAN
Tyrosine-protein kinase byk
Tyrosine-protein kinase DTK
Tyrosine-protein kinase receptor TYRO3
Tyrosine-protein kinase RSE
Tyrosine-protein kinase SKY
Tyrosine-protein kinase TIF
c MER
c mer proto oncogene tyrosine kinase
c-mer
cMER
cmer protooncogene tyrosine kinase
Eyk
MER
MER receptor tyrosine kinase
MERK
MERPEN
Mertk
MERTK c-mer proto-oncogene tyrosine kinase
MERTK_HUMAN
MGC133349
nmf12
Nyk
Proto oncogene tyrosine protein kinase MER
Proto oncogene tyrosine protein kinase MER precursor
Proto-oncogene c-Mer
Receptor tyrosine kinase MerTK
RP38
STK kinase
Tyrosine-protein kinase Mer
Molecular Weight(MW) 110 kDa/97 kDa
Cellular Localization Cell membrane.
Database Links
SwissProt ID Q06418 Q12866
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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