| Product Name | Anti-Phospho-SREBP1 (Ser396) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser396 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SREBF1 |
|---|---|
| Gene Synonyms | HMD IFAP2 SREBP1 bHLHd1 |
| Gene Full Name | sterol regulatory element binding transcription factor 1 |
| Gene Summary | This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017] |
| Alternative Names | ADD 1 bHLHd1 Class D basic helix-loop-helix protein 1 D630008H06 Processed sterol regulatory element-binding protein 1 SRBP1_HUMAN SREBF 1 SREBF1 SREBP 1 SREBP 1c SREBP-1 SREBP1 Sterol regulatory element binding protein 1 Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1 Sterol regulatory element binding transcription factor 1 Sterol regulatory element-binding transcription factor 1 |
| Molecular Weight(MW) | 122 kDa |
| Cellular Localization | Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus. |
| SwissProt ID | P36956 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
