| Gene Symbol |
NUMB
|
| Gene Synonyms |
S171 C14orf41 c14_5527 |
| Gene Full Name |
NUMB endocytic adaptor protein |
| Gene Summary |
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Alternative Names |
c14_5527 C14orf41 FLJ31314 h Numb h-Numb Numb Numb homolog (Drosophila) Numb homolog Numb protein homolog NUMB_HUMAN Protein numb homolog Protein S171 S171 |
| Molecular Weight(MW) |
71 kDa |
| Cellular Localization |
Cell membrane, Endosome, Membrane. |