| Product Name | Anti-Phospho-BRK (Tyr447) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr447 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTK6 |
|---|---|
| Gene Synonyms | BRK |
| Gene Full Name | protein tyrosine kinase 6 |
| Gene Summary | The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
| Alternative Names | Breast tumor kinase Breast tumour kinase Protein tyrosine kinase 6 Protein-tyrosine kinase 6 Ptk6 PTK6_HUMAN Tyrosine protein kinase BRK Tyrosine-protein kinase BRK |
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Cell projection, Cytoplasm, Membrane, Nucleus. |
| SwissProt ID | Q13882 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
