| Gene Symbol |
SCRIB
|
| Gene Synonyms |
CRIB1 SCRB1 SCRIB1 Vartul oSCRIB |
| Gene Full Name |
scribble planar cell polarity protein |
| Gene Summary |
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Alternative Names |
CRIB 1 CRIB1 hScrib LAP 4 LAP4 PDZ domain protein scribble Protein LAP4 Protein scribble homolog SCRB 1 SCRB1 SCRIB 1 Scrib SCRIB_HUMAN SCRIB1 Scribble Scribble homolog 1 scribbled homolog (Drosophila) Vartul |
| Molecular Weight(MW) |
175 kDa |
| Cellular Localization |
Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse. |