| Product Name | Anti-Phospho-IL-2R beta/CD122 (Tyr364) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr364 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IL2RB |
|---|---|
| Gene Synonyms | CD122 IMD63 IL15RB P70-75 |
| Gene Full Name | interleukin 2 receptor subunit beta |
| Gene Summary | The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression. [provided by RefSeq, Sep 2016] |
| Alternative Names | CD122 CD122 antigen High affinity IL 2 receptor beta subunit High affinity IL 2 receptor subunit beta High affinity IL-2 receptor subunit beta IL-2 receptor subunit beta IL-2R subunit beta IL-2RB IL15RB IL2 receptor IL2RB IL2RB_HUMAN Interleukin 2 receptor beta Interleukin-2 receptor subunit beta P70 75 P70-75 P7075 p75 |
| Molecular Weight(MW) | 61 kDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | P14784 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
