| Gene Symbol |
KLF5
|
| Gene Synonyms |
CKLF IKLF BTEB2 |
| Gene Full Name |
KLF transcription factor 5 |
| Gene Summary |
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] |
| Alternative Names |
Basic transcription element binding protein 2 Basic transcription element-binding protein 2 BTE binding protein 2 BTE-binding protein 2 BTEB 2 BTEB2 CKLF Colon krueppel like factor Colon krueppel-like factor GC box binding protein 2 GC-box-binding protein 2 IKLF Intestinal enriched krueppel like factor Intestinal-enriched krueppel-like factor KLF 5 Klf5 KLF5_HUMAN Krueppel like factor 5 Krueppel-like factor 5 Kruppel like factor 5 intestinal Transcription factor BTEB 2 Transcription factor BTEB2 |
| Molecular Weight(MW) |
51 kDa |
| Cellular Localization |
Nucleus. |