| Gene Symbol |
LCP1
|
| Gene Synonyms |
CP64 PLS2 LC64P HEL-S-37 L-PLASTIN |
| Gene Full Name |
lymphocyte cytosolic protein 1 |
| Gene Summary |
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008] |
| Alternative Names |
CP64 L plastin L-plastin Larval cuticle protein 1 LC64P LCP-1 LCP1 LPL Lplastin Lymphocyte cytosolic protein 1 Plastin 2 Plastin-2 PLS2 PLSL_HUMAN |
| Molecular Weight(MW) |
70 kDa |
| Cellular Localization |
Cell junction,Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Membrane. |