| Product Name | Anti-Phospho-FGFR4 (Tyr642) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr642 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FGFR4 |
|---|---|
| Gene Synonyms | TKF JTK2 CD334 |
| Gene Full Name | fibroblast growth factor receptor 4 |
| Gene Summary | The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017] |
| Alternative Names | CD 334 CD334 CD334 antigen fc13h 10 fc13h10 Fgfr 4 FGFR-4 Fgfr4 FGFR4_HUMAN Fibroblast growth factor receptor 4 Hydroxyaryl protein kinase JTK 2 JTK2 MGC20292 Protein tyrosine kinase TKF Tyrosine kinase related to fibroblast growth factor receptor Tyrosylprotein kinase |
| Molecular Weight(MW) | 88 kDa |
| Cellular Localization | Cell membrane,Endoplasmic reticulum,Endosome,Membrane,Secreted. |
| SwissProt ID | P22455 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
