| Gene Symbol |
RIPK1
|
| Gene Synonyms |
RIP RIP1 AIEFL IMD57 RIP-1 |
| Gene Full Name |
receptor interacting serine/threonine kinase 1 |
| Gene Summary |
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017] |
| Alternative Names |
Cell death protein RIP FLJ39204 OTTHUMP00000039163 Receptor (TNFRSF) interacting serine threonine kinase 1 receptor interacting protein 1 Receptor interacting protein Receptor interacting protein kinase 1 Receptor interacting serine threonine protein kinase 1 Receptor TNFRSF interacting serine threonine kinase 1 Receptor-interacting protein 1 Receptor-interacting serine/threonine-protein kinase 1 Rinp RIP 1 RIP Rip-1 RIP1 RIPK 1 Ripk1 RIPK1_HUMAN Serine threonine protein kinase RIP Serine/threonine-protein kinase RIP |
| Molecular Weight(MW) |
76 kDa |
| Cellular Localization |
Cell membrane,Cytoplasm,Membrane. |