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OM683723
Discount Price
OM683723-100ul
100ul
Product Profile
Product Name Anti-Phospho-TLR5 (Ser805) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser805
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TLR5
Gene Synonyms SLE1
TIL3
SLEB1
MELIOS
Gene Full Name toll like receptor 5
Gene Summary This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
Alternative Names FLJ10052
MGC126430
MGC126431
SLEB1
TIL 3
TIL3
TLR 5
Tlr5
TLR5_HUMAN
Toll like receptor 5
Toll like receptor 5 precursor
Toll-like receptor 5
Toll/interleukin 1 receptor like protein 3
Toll/interleukin-1 receptor-like protein 3
Molecular Weight(MW) 98 kDa
Cellular Localization Cell membrane,Membrane.
Database Links
SwissProt ID O60602
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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