| Gene Symbol |
GLI1
|
| Gene Synonyms |
GLI PPD1 PAPA8 |
| Gene Full Name |
GLI family zinc finger 1 |
| Gene Summary |
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| Alternative Names |
Gli 1 GLI GLI family zinc finger 1 GLI Kruppel family member 1 gli1 GLI1_HUMAN Glioma associated oncogene 1 Glioma associated oncogene homolog 1 (zinc finger protein) Glioma associated oncogene homolog Glioma-associated oncogene Oncogene GLI Zfp 5 Zfp5 Zinc finger protein GLI 1 Zinc finger protein GLI1 |
| Molecular Weight(MW) |
118 kDa |
| Cellular Localization |
Cell projection,Cytoplasm,Nucleus. |