| Product Name | Anti-Phospho-DR6 (Tyr460) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr460 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFRSF21 |
|---|---|
| Gene Synonyms | DR6 CD358 BM-018 |
| Gene Full Name | TNF receptor superfamily member 21 |
| Gene Summary | This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013] |
| Alternative Names | TNFRSF 21 BM 018 BM018 CD358 Death receptor 6 DR 6 DR6 MGC31965 OTTHUMP00000039915 TNFR related death receptor 6 TNFRSF21 TNFRSF21 protein TNR21_HUMAN Tumor necrosis factor receptor superfamily member 21 Tumor necrosis factor receptor superfamily member 21 precursor |
| Molecular Weight(MW) | 72 kDa |
| Cellular Localization | Cell membrane,Membrane. |
| SwissProt ID | O75509 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
