| Gene Symbol |
RPS6KA4
|
| Gene Synonyms |
MSK2 RSK-B S6K-alpha-4 |
| Gene Full Name |
ribosomal protein S6 kinase A4 |
| Gene Summary |
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
| Alternative Names |
90 kDa ribosomal protein S6 kinase 4 EC 2.7.11.1 KS6A4_HUMAN Mitogen and stress activated protein kinase 2 Nuclear mitogen and stress activated protein kinase 2 Nuclear mitogen- and stress-activated protein kinase 2 Ribosomal protein kinase B Ribosomal protein S6 kinase 90kD polypeptide 4 Ribosomal protein S6 kinase 90kDa polypeptide 4 Ribosomal protein S6 kinase alpha 4 Ribosomal protein S6 kinase alpha-4 RPS6KA4 RSKB S6K-alpha-4 |
| Molecular Weight(MW) |
86 kDa |
| Cellular Localization |
Nucleus. |