| Gene Symbol |
STAM2
|
| Gene Synonyms |
Hbp STAM2A STAM2B |
| Gene Full Name |
signal transducing adaptor molecule 2 |
| Gene Summary |
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008] |
| Alternative Names |
DKFZp564C047 Hbp Hrs-binding protein HSE1 homolog Signal transducing adapter molecule 2 Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 Signal transducing adaptor molecule 2A Signal transducing adaptor molecule 2B Signal transducing adaptor molecule STAM like protein containing SH3 and ITAM domains 2 STAM-2 Stam2 STAM2_HUMAN STAM2A STAM2B |
| Molecular Weight(MW) |
58 kDa |
| Cellular Localization |
Cytoplasm,Endosome,Membrane. |