| Gene Symbol |
CDK1
|
| Gene Synonyms |
CDC2 CDC28A P34CDC2 |
| Gene Full Name |
cyclin dependent kinase 1 |
| Gene Summary |
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2023] |
| Alternative Names |
Cdc2 related protein kinase cdc2-related protein kinase CDC28 CDC2A Cdk 2 CDK1 CDK2 CDK2_HUMAN CDKN2 Cell devision kinase 2 Cell division protein kinase 2 Cyclin dependent kinase 2 cyclin dependent kinase 2-alpha Cyclin-dependent kinase 2 kinase Cdc2 MPF p33 protein kinase p33(CDK2) |
| Molecular Weight(MW) |
34 kDa |
| Cellular Localization |
Cytoplasm,Cytoskeleton,Mitochondrion,Nucleus. |