| Gene Symbol |
TPH2
|
| Gene Synonyms |
NTPH ADHD7 |
| Gene Full Name |
tryptophan hydroxylase 2 |
| Gene Summary |
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016] |
| Alternative Names |
MGC138871 ADHD7 FLJ37295 MGC138872 Neuronal tryptophan hydroxylase NTPH TPH 2 Tph2 TPH2_HUMAN Tryptophan 5-hydroxylase 2 Tryptophan 5-monooxygenase 2 Tryptophan hydroxylase 2 |
| Molecular Weight(MW) |
56 kDa |
| Cellular Localization |
cytosol, neuron projection. |