| Product Name | Anti-Phospho-APLP2 (Tyr755) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr755 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | APLP2 |
|---|---|
| Gene Synonyms | APPH APPL2 CDEBP APLP-2 |
| Gene Full Name | amyloid beta precursor like protein 2 |
| Gene Summary | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Alternative Names | amyloid beta (A4) precursor like protein 2 Amyloid like protein 2 Amyloid precursor protein homolog HSD 2 amyloid precursor protein homolog HSD2 Amyloid protein homolog Amyloid-like protein 2 APLP-2 Aplp2 APLP2_HUMAN APPH APPL2 CDEBP CDEI box binding protein CDEI box-binding protein |
| Molecular Weight(MW) | 87 kDa |
| Cellular Localization | Cell membrane, Nucleus. |
| SwissProt ID | Q06481 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
