DCC-interacting protein 13-beta, Dip13-beta, Adapter protein containing PH domain, PTB domain and leucine zipper motif 2, APPL2, DIP13B
Product description
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.1) Chial, H.J., et al. PLoS ONE(8), E12471 (2010) :
Immunogen
This APPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human APPL2.
Western blot analysis of APPL2 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in NCI-H292 cell line lysate.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.