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APLP2 Antibody (C-term)

Catalog Number:OM226660
OM226660
Discount Price
OM226660-100ul
1~2 Week
100ul
OM226660-50ul
50ul
OM226660-20ul
20ul
1~2 Week
Product Profile
Product Name APLP2 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias APLP2; APPL2; Amyloid-like protein 2; APPH; Amyloid protein homolog; CDEI box-binding protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms APPL2
Alternative Names APLP2
APPL2
Amyloid-like protein 2
APPH
Amyloid protein homolog
CDEI box-binding protein
Molecular Weight(MW) 86956 Da
Function May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity)
Tissue Specificity Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues
Cellular Localization Cell membrane; Single-pass type I membrane protein (Potential). Nucleus (Potential)
Database Links
Entrez Gene 334
Nucleotide Accession NP_001135748.1 NP_001633.1
Application

Application

APLP2 Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the APLP2 antibody detected the APLP2 protein (arrow).

Application

APLP2 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the APLP2 antibody detected the APLP2 protein (arrow).

Application

APLP2 Antibody (C-term) (AP14673b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of APLP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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