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WB
Western blot analysis of MAP2 in mouse brain , rat brain lysates and using MAP2 Goat pAb.IF
Immunofluorescence analysis of MAP2(Green) in mouse brain tissue using MAP2 Goat pAb, and DAPI(Blue)IHC
Immunohistochemistry of Paraffin-embedded human lung tissue sections using the antibody MAP2 Goat pAb at a dilution of 1/50. Heat-induced epitope retrieval was performed using sodium citrate buffer (pH 6.0).IHC
Immunohistochemistry of Paraffin-embedded mouse brain using the antibody MAP2 Goat pAb at a dilution of 1/50. Heat-induced epitope retrieval was performed using sodium citrate buffer (pH 6.0).| Product Name | MAP2 Goat pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human MAP2 |
| Modification | Unmodified |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Goat |
| Tested Applications | IHCWBIF |
| WB:1:500-1:1000 IHC:1:100-1:500 IF-P:1:100-1:500 ICC/IF:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity Purified |
| Gene Symbol | MAP2 |
|---|---|
| Gene Synonyms | MAP-2 MAP2A MAP2B MAP2C |
| Gene Full Name | microtubule associated protein 2 |
| Gene Summary | This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010] |
| Molecular Weight(MW) | 280 kDa |
| Function | MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD). |
| Cellular Localization | Cell projection,Cytoplasm,Cytoskeleton,Microtubule |
WB
Western blot analysis of MAP2 in mouse brain , rat brain lysates and using MAP2 Goat pAb.
IF
Immunofluorescence analysis of MAP2(Green) in mouse brain tissue using MAP2 Goat pAb, and DAPI(Blue)
IHC
Immunohistochemistry of Paraffin-embedded human lung tissue sections using the antibody MAP2 Goat pAb at a dilution of 1/50. Heat-induced epitope retrieval was performed using sodium citrate buffer (pH 6.0).
IHC
Immunohistochemistry of Paraffin-embedded mouse brain using the antibody MAP2 Goat pAb at a dilution of 1/50. Heat-induced epitope retrieval was performed using sodium citrate buffer (pH 6.0).| Application Notes | WB:1:500-1:1000 IHC:1:100-1:500 IF-P:1:100-1:500 ICC/IF:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS, 50% glycerol, 0.05% Proclin 300, 0.08%BSA |
