Predicted to enable several functions, including cation binding activity,oxygen binding activity,and tyrosine 3-monooxygenase activity. Involved in eye development and visual perception. Acts upstream of or within several processes, including dopamine biosynthetic process from tyrosine,dopaminergic synaptic transmission,and learning or memory. Located in several cellular components, including axon,perikaryon,and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system,cardiovascular system,eye,genitourinary system,and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease,Parkinsonism,heroin dependence,hypertension,and obesity. Orthologous to human TH (tyrosine hydroxylase). [provided by Alliance of Genome Resources, Jul 2025]
Alternative Names
TYH DYT5b Tyrosine 3-Monooxygenase Dystonia 14
Application
WB
Western Blot,Samples: Lane1: Rat Cerebrum lysate,Lane2: Rat Adrenal gland lysate,Primary Ab: 0.2µg/ml Mouse Anti-Rat TH Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes
WB: 0.01-2µg/mL
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.