| Product Name | Rat TNF-alpha Recombinant Protein |
|---|---|
| Species Reactivity | Rat |
| Gene Symbol | Tnf |
| Gene Synonyms | Tnfa RATTNF TNF-alpha |
| Gene Full Name | tumor necrosis factor |
| Gene Summary | Enables tumor necrosis factor receptor binding activity. Involved in several processes, including negative regulation of transport; positive regulation of cell communication; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within positive regulation of interleukin-6 production. Located in external side of plasma membrane; extracellular space; and neuronal cell body. Is active in extracellular region. Used to study several diseases, including cerebrovascular disease (multiple); liver disease (multiple); peptic esophagitis; perinatal necrotizing enterocolitis; and periventricular leukomalacia. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); congestive heart failure (multiple); liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); liver disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor). [provided by Alliance of Genome Resources, Apr 2025] |
