| Product Name | Human ICAM-3 Recombinant Protein |
|---|---|
| Species Reactivity | Human |
| Gene Symbol | ICAM3 |
| Gene Synonyms | CD50 CDW50 ICAM-R |
| Gene Full Name | intercellular adhesion molecule 3 |
| Gene Summary | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. |
