| Product Name | Human STAT2 Recombinant protein |
|---|---|
| Species Reactivity | Human |
| Gene Symbol | STAT2 |
| Gene Synonyms | P113 IMD44 ISGF-3 PTORCH3 STAT113 |
| Gene Full Name | signal transducer and activator of transcription 2 |
| Gene Summary | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. |
