Western blot
Host: Rabbit Target Name: LDLR Sample Tissue: Fetal Heart lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-LDLR Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FH, FHC, LDLCQ2 |
| Immunogen | The immunogen for Anti-LDLR antibody is: synthetic peptide directed towards the C-terminal region of Human LDLR |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LDLR |
|---|---|
| Gene Synonyms | FH FHC LDLCQ2 |
| Gene Full Name | low density lipoprotein receptor |
| Gene Summary | The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants. |
| Alternative Names | FH FHC LDLCQ2 |
| Molecular Weight(MW) | 75kDa |
| Sequence | 682 amino acids |
| Entrez Gene | 3949 |
|---|---|
| SwissProt ID | P01130-2 |
| Protein Accession | NP_001182732 |
Western blot
Host: Rabbit Target Name: LDLR Sample Tissue: Fetal Heart lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM111727