The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. CD8 is thought to play a role in the process of T-cell mediated killing.
Immunogen
peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBICCIHCFC
WB:1:500
Species Reactivity
Mouse
Concentration
1 mg/mL.
Target Information
Alternative Names
CD8 antibody
CD8 antigen alpha polypeptide (p32) antibody
CD8a antibody
CD8a antigen antibody
CD8a molecule antibody
CD8A_HUMAN antibody
Leu2 antibody
Leu2 T lymphocyte antigen antibody
MAL antibody
OKT8 T cell antigen antibody
p32 antibody
T cell antigen Leu2 antibody
T cell co receptor antibody
T-cell surface glycoprotein CD8 alpha chain antibody
T-lymphocyte differentiation antigen T8/Leu-2 antibody
T8 T cell antigen antibody
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