CLOCK

Catalog Number：OM638893

  • Fig1: Western blot analysis on different lysates using anti-CLOCK rabbit polyclonal antibody. Positive control: Lane 1: PC-12 Lane 2: NIH/3T3 Lane 3: Hela Lane 4: MCF-7 Lane 5: Mouse brain Lane 6: Mouse kidney

  • Fig2: Immunocytochemical staining of PC-3M cells using anti-CLOCK rabbit polyclonal antibody.

  • Fig3: Immunocytochemical staining of SW480 cells using anti-CLOCK rabbit polyclonal antibody.

  • Fig4: Immunocytochemical staining of Hela cells using anti-CLOCK rabbit polyclonal antibody.

  • Fig5: Immunocytochemical staining of 293 cells using anti-CLOCK rabbit polyclonal antibody.

  • Fig6: Immunohistochemical analysis of paraffin- embedded human kidney tissue using anti-CLOCK rabbit polyclonal antibody.

  • Fig7: Immunohistochemical analysis of paraffin- embedded mouse testis tissue using anti-CLOCK rabbit polyclonal antibody.

  • Fig8: Immunohistochemical analysis of paraffin- embedded mouse skeletal muscle tissue using anti-CLOCK rabbit polyclonal antibody.

  • Fig9: Immunohistochemical analysis of paraffin- embedded human colon cancer tissue using anti-CLOCK rabbit polyclonal antibody.

  • Fig10: Flow cytometric analysis of Hela cells with CLOCK antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.

Product Profile

Product Name CLOCK
Antibody Type Primary Antibodies
Product description 
Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. Clock, a member of the basic-helix-loop-helix-PAS (bHLH-PAS) family of transcription factors, has also been identified as having circadian function. Mutations within the Clock gene have been shown to increase the length of the endogenous period and to cause a loss of rhythmicity of circadian oscillations. Clock contains a DNA-binding domain, a protein dimerization domain and a glutamine-rich C-terminal region, which indicates transactivation capabilities. It has been speculated that Clock may regulate circadian rhythmicity in combination with other proteins such as Per. Per is also a PAS-domain containing protein that exhibits circadian function. Highest expression of Clock is seen in the hypothalamus and the eye.
Immunogen 
peptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFC
WB:1:1,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity

HumanMouseRat
Concentration 1 mg/mL.

Target Information

Alternative Names
bHLHe8 antibody Circadian locomoter output cycles kaput protein antibody Circadian locomoter output cycles protein kaput antibody Circadian Locomotor Output Cycles Kaput antibody Circadium Locomotor Output Cycles Kaput antibody Class E basic helix-loop-helix protein 8 antibody CLOCK antibody Clock circadian regulator antibody Clock homolog antibody Clock protein antibody CLOCK_HUMAN antibody hCLOCK antibody KIAA0334 antibody
Molecular Weight(MW) 95kDa
Cellular Localization Cytoplasm, Nucleus

Database Links

SwissProt ID O15516

Application

  • Application

    Fig1: Western blot analysis on different lysates using anti-CLOCK rabbit polyclonal antibody. Positive control: Lane 1: PC-12 Lane 2: NIH/3T3 Lane 3: Hela Lane 4: MCF-7 Lane 5: Mouse brain Lane 6: Mouse kidney

  • Application

    Fig2: Immunocytochemical staining of PC-3M cells using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig3: Immunocytochemical staining of SW480 cells using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig4: Immunocytochemical staining of Hela cells using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig5: Immunocytochemical staining of 293 cells using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig6: Immunohistochemical analysis of paraffin- embedded human kidney tissue using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig7: Immunohistochemical analysis of paraffin- embedded mouse testis tissue using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig8: Immunohistochemical analysis of paraffin- embedded mouse skeletal muscle tissue using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig9: Immunohistochemical analysis of paraffin- embedded human colon cancer tissue using anti-CLOCK rabbit polyclonal antibody.

  • Application

    Fig10: Flow cytometric analysis of Hela cells with CLOCK antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.

Positive Control Hela, 293, PC-12, NIH/3T3, SW480, PC-3M, human kidney tissue, mouse testis tissue, human colon cancer tissue, mouse skeletal muscle tissue.
Application Notes
WB:1:1,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Additional Information

Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Submit an review for OM638893
Submit an review for OM638893
  • Catalog Number: OM638893
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: Out of stock
  • Lead time: 4~6 Week

  • Quantity:
    - +
  • Shipping to (Please select)
Add to cart
Add to Wishlist
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.
PRODUCT CATEGORIES
Primary antibodies Secondary antibodies Tags antibodies Flow cytometry antibodies
SUPPORT
Catalogs Newsletter Order Online Buying FAQs Distributor
COMPANY
Profile Strategy Careers
CONTACT
Contact us

2013 © Omnimabs , All Rights Reserved.